@article{Hamdani_Djide_Arif_2022, title={Incidence of Klebsiella pneumoniae producing Metallo Beta-Lactamase (MBL) at RSUP Dr. Wahidin Sudirohusodo Makassar}, volume={3}, url={http://jffk.unram.ac.id/index.php/sjp/article/view/111}, DOI={10.29303/sjp.v3i1.111}, abstractNote={<p>Bacterial resistance to antibiotic is one of the factors triggering infection therapy failure. This study was conducted to determine the prevalence of carbapenem-resistance Klebsiella pneumoniae infection and the phenotype of <em>carbapenem-resistant Metallo-Beta-Lactamase (MBL)-producing Klebsiella pneumoniae isolates </em>at RSUP Dr. Wahidin Sudirohusodo Makassar. This study included <em>Klebsiella pneumoniae </em>identification on each infectious patient’s isolates. The sensitivity test of antibiotics, phenotype confirmatory test, and MBL phenotypic test were conducted using agar diffusion Kirby-Bauer, Vitek-2-Compact, and Double Disc Synergy Test (DDST) method, respectively. As the result, the antibiotic sensitivity test using the Vitek-2-Compact method on 50 clinical samples (pus, sputum, blood. tissue, urine, brain fluid, and feces) found that 10 isolates (20%) were resistant to carbapenem.  The phenotypic test using the Double Disc Synergy Test (DDST) method found that carbapenem-resistant isolates caused by the production of <em>Metallo Beta Lactamase (MBL) enzymes </em>were 2 isolates or 20% of the total carbapenem-resistant isolates.</p>}, number={1}, journal={Sasambo Journal of Pharmacy}, author={Hamdani, Muhammad Jen and Djide, Natsir and Arif, Mansyur}, year={2022}, month={Apr.}, pages={6–10} }