Vol. 3 No. 1 (2022): April
Open Access
Peer Reviewed

Potensi interaksi obat pada pasien skizofrenia di Rumah Sakit Jiwa Mutiara Sukma tahun 2020

Authors

Virnia Wanda Utami , Mudrikah Darajati , Candra Eka Puspitasari

DOI:

10.29303/sjp.v3i1.151

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Received: Mar 04, 2022
Accepted: Apr 25, 2022
Published: Apr 28, 2022

Abstract

Schizophrenia is a chronic mental disorder characterized by distortions in thinking and behavior. Schizophrenic patients receive antipsychotic therapy (main) and non-antipsychotic (supportive) for a long time. Prescription drugs are given either single or in combination, that can possible for drug interactions. This study objective to determine the potential drug-drug interactions in schizophrenic patients. The design of this study was cross-sectional with purposive sampling technique. The data used is secondary data from the medical records of inpatient schizophrenia patients at the Mutiara Sukma Mental Hospital NTB in 2020 with a retrospective method. The sample data obtained were 109 medical records. The results showed that there were 82,2% of drug interaction cases, namely the combination of risperodone and lorazepam. The number of major interaction cases is 24,2%, moderate is 72,1% and minor is 3,6%. The high incidence of drug interactions in schizophrenic patients requires closely monitored.

Keywords:

Schizophrenia, Drug Interactions, Antipsychotics

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Author Biographies

Virnia Wanda Utami, Universitas Mataram

Mudrikah Darajati, Mutiara Sukma Mental Hospital NTB

Candra Eka Puspitasari, Universitas Mataram

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How to Cite

Utami, V. W., Darajati, M., & Puspitasari, C. E. (2022). Potensi interaksi obat pada pasien skizofrenia di Rumah Sakit Jiwa Mutiara Sukma tahun 2020. Sasambo Journal of Pharmacy, 3(1), 36–42. https://doi.org/10.29303/sjp.v3i1.151