Vol. 4 No. 1 (2023): April
Open Access
Peer Reviewed

Identifikasi Drug Related Problems (DRPs) pasien diabetes mellitus tipe 2 yang terkonfirmasi Covid-19

Authors

Khaeditama Purnama Anwar , EM Sutrisna

DOI:

10.29303/sjp.v4i1.218

Downloads

Received: Feb 21, 2023
Accepted: Mar 20, 2023
Published: Apr 30, 2023

Abstract

Drug Related Problems (DRPs) are events or circumstances related to drug therapy that actually or have the potential to interfere with the desired therapeutic outcome. This study aims to identify the incidence of DRPs in patients with type 2 diabetes mellitus who are confirmed to have Covid-19. This research is a type of observational research with a cross sectional design. Data collection was carried out retrospectively by tracing patient medical record data. The number of patients who met the researcher’s inclusion criteria was 125 patients and on average each patient had DRPs. The categories of DRPs that occurred were indications without drugs for 57 patients (45,6%), drugs without indications for 11 patients (8,8%), inappropriate drug selection for 45 patients (36%), inadequate doses for 28 patients (22,4%), overdosage in 46 patients (36,8%), and drug interactions in 88 patients (70,4%)

Keywords:

Diabetes mellitus type 2, Covid-19, Drug Related Problems

References

Belice, T., & Demir, I. (2020). The gender differences as a risk factor in diabetic patients with Covid-19, 12 (6). 10.18502/ijm.v12i6.5038

Bergamaschi, G., Borrelli de Andreis, F., Aronico, N., Lenti, M. V., Barteselli, C., Merli, S., Pellegrino, I., Coppola, L., Cremonte, E. M., Croce, G., Mordà , F., Lapia, F., Ferrari, S., Ballesio, A., Parodi, A., Calabretta, F., Ferrari, M. G., Fumoso, F., Gentile, A., Stefani, D. (2021). Anemia in patients with Covid-19: pathogenesis and clinical significance. Clinical and Experimental Medicine, 21 (2), 239–246. https://doi.org/10.1007/s10238-020-00679-4

Guo, W., Li, M., Dong, Y., Zhou, H., Zhang, Z., Tian, C., Qin, R., Wang, H., Shen, Y., Du, K., Zhao, L., Fan, H., Luo, S., & Hu, D. (2020). Diabetes is a risk factor for the progression and prognosis of Covid-19. Diabetes/Metabolism Research and Reviews, 36 (7). https://doi.org/10.1002/dmrr.3319

Hanutami, B., & Dandan, K. L. (2019). Identifikasi potensi interaksi antar obat pada resep umum di apotek kimia farma 58 kota bandung bulan april 2019. Farmaka, 17 (2), 57-64. https://doi.org/10.24198/jf.v17i2.22956

International Diabetes Federation. (2019). 463 million people living with diabetes. IDF Diabetes Atlas

James, P. A., Oparil, S., Carter, B. L., Cushman, W. C., Dennison-Himmelfarb, C., Handler, J., Lackland, D. T., LeFevre, M. L., MacKenzie, T. D., Ogedegbe, O., Smith, S. C., Svetkey, L. P., Taler, S. J., Townsend, R. R., Wright, J. T., Narva, A. S., & Ortiz, E. (2014). 2014 Evidence-based guideline for the management of high blood pressure in adults: Report from the panel members appointed to the Eighth Joint National Committee (JNC 8). In JAMA (Vol. 311, Issue 5, pp. 507–520). American Medical Association. https://doi.org/10.1001/jama.2013.284427

Karyono, D. R., & Wicaksana, A. L. (2020). Current prevalence, characteristics, and comorbidities of patients with Covid-19 in Indonesia. Journal of Community Empowerment for Health, 3 (2), 77. https://doi.org/10.22146/jcoemph.57325

Kautzky-Willer, A., Harreiter, J., & Pacini, G. (2016). Sex and gender differences in risk, pathophysiology and complications of type 2 diabetes mellitus. In Endocrine Reviews, 37 (3), 278-316. Endocrine Society. https://doi.org/10.1210/er.2015-1137

Kautzky-Willer, A. (2021). Does diabetes mellitus mitigate the gender gap in Covid-19 mortality? European Journal of Endocrinology, 185 (5), 13–17. https://doi.org/10.1530/EJE-21-0721

Kemenkes RI. (2021). Situasi indonesia 2 peta situasi di indonesia CFR dan recovery rate. https://infeksiemerging.kemkes.go.id

Korytkowski, M., Antinori-Lent, K., Drincic, A., Hirsch, I. B., Mcdonnell, M. E., Rushakoff, R., Muniyappa, R.,& Korytkowski, M. T. (2020). A Pragmatic Approach to Inpatient Diabetes Management during the Covid-19 Pandemic. 10.1210/clinem/dgaa342.

Mantovani, A., Byrne, C. D., Zheng, M. H., & Targher, G. (2020). Diabetes as a risk factor for greater Covid-19 severity and in-hospital death: A meta-analysis of observational studies. Nutrition, Metabolism and Cardiovascular Diseases, 30 (8), 1236–1248. https://doi.org/10.1016/j.numecd.2020.05.014

Mordarska, K., & Godziejewska-Zawada, M. (2017). Diabetes in the elderly. In Przeglad Menopauzalny, 16 (2), 38–43. Termedia Publishing House Ltd. https://doi.org/10.5114/pm.2017.68589

Pasquel, F. J., Fayfman, M., & Umpierrez, G. E. (2019). Debate on Insulin vs Non-insulin Use in the Hospital Setting-Is It Time to Revise the Guidelines for the Management of Inpatient Diabetes? In Current Diabetes Reports, 19 (9), 65. https://doi.org/10.1007/s11892-019-1184-8

Peng, M., He, J., Xue, Y., Yang, X., Liu, S., & Gong, Z. (2021). Role of Hypertension on the Severity of Covid-19: A Review. 10.1097/FJC.0000000000001116

Sardu, C., D’Onofrio, N., Balestrieri, M. L., Barbieri, M., Rizzo, M. R., Messina, V., Maggi, P., Coppola, N., Paolisso, G., &

Marfella, R. (2020). Outcomes in patients with hyperglycemia affected by Covid-19 : can we do more on glycemic control?. Diabetes Care, 43 (7), 1408-1415. 10.2337/dc20-0723

Wibisono, S., Soetmadji, D. W., Pranoto, A., Mardianto., Shahab, A., Karimi, J., Taringan, T. J. E., Pemanyun, T. G. D., Pramono, R. B., Fajari, N. M. (2021). Pedoman Petunjuk Praktis Terapi Insulin Pada Pasien Diabetes Mellitus. PB Perkeni.

World Health Organization. (2016). Global report on diabetes. WHO

Wu, J., Zhang, J., Sun, X., Wang, L., Xu, Y., Zhang, Y., Liu, X., & Dong, C. (2020). Influence of diabetes mellitus on the severity and fatality of SARS-CoV-2 (Covid-19) infection. Diabetes, Obesity and Metabolism, 22 (10), 1907-1914. 10.1111/dom.141051054-1062. https://doi.org/10.1016/S0140-6736(20)30566-3

Zhou, F., Yu, T., Du, R., Fan, G., Liu, Y., Liu, Z., Xiang, J., Wang, Y., Song, B., Gu, X., Guan, L., Wei, Y., Li, H., Wu, X., Xu, J., Tu, S., Zhang, Y., Chen, H., & Cao, B. (2020). Clinical course and riskfactors for mortality of adult inpatients with Covid-19 in wuhan, china : a retrospective cohort study. The Lancet, 395 (10229), 1054-1062. https://doi.org/10.1016/S0140-6736(20)30566-3

Zhu, N., Zhang, D., Wang, W., Li, X., Yang, B., Song, J., Zhao, X., Huang, B., Shi, W., Lu, R., Niu, P., Zhan, F., Ma, X., Wang, D., Xu, W., Wu, G., Gao, G. F., & Tan, W. (2020). A novel coronavirus from patients with pneumonia in china, 2019. New England Journal of Medicine, 382 (8), 727-733. 10.1056/NEJMoa2001017

Author Biography

Khaeditama Purnama Anwar, Universitas Muhammadiyah Surakarta

Downloads

Download data is not yet available.

How to Cite

Anwar, K. P., & Sutrisna, E. (2023). Identifikasi Drug Related Problems (DRPs) pasien diabetes mellitus tipe 2 yang terkonfirmasi Covid-19. Sasambo Journal of Pharmacy, 4(1), 19–23. https://doi.org/10.29303/sjp.v4i1.218