Peranan ACE-Inhibitor pada penyakit jantung bawaan

Yusra Pintaningrum; Alit Utamayasa; Mahrus A. Rahman; Teddy Ontoseno; Ketut Angga Aditya Putra Pramana

doi:10.29303/sjp.v4i2.240

Peranan ACE-Inhibitor pada penyakit jantung bawaan

Penulis

Yusra Pintaningrum , Alit Utamayasa , Mahrus A. Rahman , Teddy Ontoseno , Ketut Angga Aditya Putra Pramana

DOI:

10.29303/sjp.v4i2.240

Diterbitkan:

2023-09-30

Terbitan:

Vol 4 No 2 (2023): September

Kata Kunci:

ACE inhibitors, congenital heart disease

Articles

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PDF (English)

Cara Mengutip

Pintaningrum, Y., Utamayasa, A., Rahman, M. A., Ontoseno, T., & Pramana, K. A. A. P. (2023). Peranan ACE-Inhibitor pada penyakit jantung bawaan. Sasambo Journal of Pharmacy, 4(2), 69–76. https://doi.org/10.29303/sjp.v4i2.240

Unduh Sitasi

Abstrak

Angiotensin-converting enzyme inhibitors have been shown to have the broadest impact of any drug in cardiovascular medicine. Dual role of ACE inhibitors, both preventing and treating cardiovascular disease. ACE inhibitors have an indirect effect on primary prevention by lessening hypertension and decreasing left ventricular hypertrophy, especially in patients with cardiac failure. In children, the causes of cardiac failure are significantly different and many cases are due to congenital malformations, such as left-to-right- shunts. In these patients, the function of both the right and the left ventricles will be affected and these children suffer from high-output cardiac failure. Therefore, in carefully selected patients with congenital heart disease, the response to systemic afterload reduction with ACE inhibitors appears favorable. Nevertheless, a more comprehensive controlled trial to assess the hemodynamic and functional effects of ACE inhibitors in such patients should be undertaken.

Referensi

Castaldi, B., Cuppini, E., Fumanelli, J., Di Candia, A., Sabatino, J., Sirico, D., Vida, V., Padalino, M., & Di Salvo, G. (2023). Chronic Heart Failure in Children: State of the Art and New Perspectives. Journal of Clinical Medicine, 12(7). https://doi.org/10.3390/jcm12072611

Dolezal T. (2006). Imidapril in heart failure. Journal of the renin-angiotensin-aldosterone system: JRAAS, 7(3), 146–154. https://doi.org/10.3317/jraas.2006.024

Faisal, M., Cawello, W., & Laeer, S. (2021). Clinical Pharmacokinetics of Enalapril and Enalaprilat in Pediatric Patients—A Systematic Review. Frontiers in Pediatrics, 9(February), 1–9. https://doi.org/10.3389/fped.2021.611322

Handoko, M. L., De Man, F. S., Allaart, C. P., Paulus, W. J., Westerhof, N., & Vonk-Noordegraaf, A. (2010). Perspectives on novel therapeutic strategies for right heart failure in pulmonary arterial hypertension: Lessons from the left heart. European Respiratory Review, 19(115), 72–82. https://doi.org/10.1183/09059180.00007109

Hemnes, A. R., Rathinasabapathy, A., Austin, E. A., Brittain, E. L., Carrier, E. J., Chen, X., Fessel, J. P., Fike, C. D., Fong, P., Fortune, N., Gerszten, R. E., Johnson, J. A., Kaplowitz, M., Newman, J. H., Piana, R., Pugh, M. E., Rice, T. W., Robbins, I. M., Wheeler, L., … West, J. (2018). A potential therapeutic role for angiotensin-converting enzyme 2 in human pulmonary arterial hypertension. European Respiratory Journal, 51(6). https://doi.org/10.1183/13993003.02638-2017

Lee, J. Y. (2010). Clinical presentations of critical cardiac defects in the newborn: Decision making and initial management. Korean Journal of Pediatrics, 53(6), 669–679. https://doi.org/10.3345/kjp.2010.53.6.669

Ma, Z. S., Ma, S. J., Dong, M. F., Wang, J. T., & Wang, L. X. (2009). Effect of captopril on pulmonary artery pressure following corrective surgery for tetralogy of fallot. Journal of Cardiac Surgery, 24(5), 553–557. https://doi.org/10.1111/j.1540-8191.2009.00873.x

Masarone, D., Valente, F., Rubino, M., Vastarella, R., Gravino, R., Rea, A., Russo, M. G., Pacileo, G., & Limongelli, G. (2017). Pediatric Heart Failure: A Practical Guide to Diagnosis and Management. Pediatrics and Neonatology, 58(4), 303–312. https://doi.org/10.1016/j.pedneo.2017.01.001

Mital, S., Chung, W. K., Colan, S. D., Sleeper, L. A., Manlhiot, C., Arrington, C. B., Cnota, J. F., Graham, E. M., Mitchell, M. E., Goldmuntz, E., Li, J. S., Levine, J. C., Lee, T. M., Margossian, R., & Hsu, D. T. (2012). NIH Public Access. 123(21), 2353–2362. https://doi.org/10.1161/CIRCULATIONAHA.110.004341.Renin-Angiotensin-Aldosterone

Okutan, V., Kürekçi, A. E., Sarici, S. Ü., Atay, A. A., Yozgat, Y., Azik, F., Lenk, M. K., & Özcan, O. (2008). Neutrophil hypersegmentation in children receiving angiotensin converting enzyme inhibitors. Turkish Journal of Pediatrics, 50(5), 438–442.

Rao P. S. (2021). Single Ventricle-A Comprehensive Review. Children (Basel, Switzerland), 8(6), 441. https://doi.org/10.3390/children8060441

Raza, S., Aggarwal, S., Jenkins, P., Kharabish, A., Anwer, S., Cullington, D., Jones, J., Dua, J., Papaioannou, V., Ashrafi, R., & Moharem-Elgamal, S. (2023). Coarctation of the Aorta: Diagnosis and Management. Diagnostics, 13(13), 2189. https://doi.org/10.3390/diagnostics13132189

Roche, S. L., Timberlake, K., Manlhiot, C., Balasingam, M., Wilson, J., George, K., Mccrindle, B. W., & Kantor, P. F. (2016). Angiotensin-Converting Enzyme Inhibitor Initiation and Dose Uptitration in Children With Cardiovascular Disease: A Retrospective Review of Standard Clinical Practice and a Prospective Randomized Clinical Trial. Journal of the American Heart Association, 5(5), 1–11. https://doi.org/10.1161/JAHA.116.003230

Seale, A. N., Uemura, H., Webber, S. A., Partridge, J., Roughton, M., Ho, S. Y., McCarthy, K. P., Jones, S., Shaughnessy, L., Sunnegardh, J., Hanseus, K., Berggren, H., Johansson, S., Rigby, M. L., Keeton, B. R., & Daubeney, P. E. F. (2010). Total anomalous pulmonary venous connection: Morphology and outcome from an international population-based study. Circulation, 122(25), 2718–2726. https://doi.org/10.1161/CIRCULATIONAHA.110.940825

Soares, A. M. (2018). Mortality for critical congenital heart diseases and associated risk factors in newborns. A cohort study. Arquivos Brasileiros de Cardiologia, 111(5), 674–675. https://doi.org/10.5935/abc.20180203

Towbin, J. A. (2010). Preface: Heart Failure in Children. Heart Failure Clinics, 6(4). https://doi.org/10.1016/j.hfc.2010.06.006

Utamayasa, A., Rahman, M. A., Ontoseno, T., & Budiono. (2020). Comparison of angiotensin-converting enzyme inhibitor (ACEI) and angiotensin receptor blocker (ARB) for heart failure treatment in congenital heart diseases with left-to-right shunt. Indonesian Biomedical Journal, 12(1), 62–68. https://doi.org/10.18585/INABJ.V12I1.997

Varela-Chinchilla, C. D., Sánchez-Mejía, D. E., & Trinidad-Calderón, P. A. (2022). Congenital Heart Disease: The State-of-the-Art on its Pharmacological Therapeutics. Journal of Cardiovascular Development and Disease, 9(7). https://doi.org/10.3390/jcdd9070201

Warnes, C. A. (2006). Transposition of the great arteries. Circulation, 114(24), 2699–2709. https://doi.org/10.1161/CIRCULATIONAHA.105.592352

Wu, W., He, J., & Shao, X. (2020). Incidence and mortality trend of congenital heart disease at the global, regional, and national level, 1990-2017. Medicine (United States), 99(23). https://doi.org/10.1097/MD.0000000000020593

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Peranan ACE-Inhibitor pada penyakit jantung bawaan

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Diterbitkan:

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