Qualitative and quantitative analysis of prednisone chemical content in rheumatic herbs in Magelang Region

Riza Nur Afifah; Arief Kusuma  Wardani; Tiara Mega Kusuma

doi:10.29303/sjp.v6i1.358

Qualitative and quantitative analysis of prednisone chemical content in rheumatic herbs in Magelang Region

Penulis

Riza Nur Afifah , Arief Kusuma Wardani , Tiara Mega Kusuma

DOI:

10.29303/sjp.v6i1.358

Diterbitkan:

2025-04-30

Terbitan:

Vol 6 No 1 (2025): April

Kata Kunci:

BKO Prednisone, KLT, UV-Vis Spectrophotometry

Articles

##submission.downloads##

PDF (English)

Cara Mengutip

Afifah, R. N., Wardani, A. K. ., & Kusuma, T. M. (2025). Qualitative and quantitative analysis of prednisone chemical content in rheumatic herbs in Magelang Region. Sasambo Journal of Pharmacy, 6(1), 1–6. https://doi.org/10.29303/sjp.v6i1.358

Unduh Sitasi

Abstrak

Currently, there is a phenomenon that shows that many herbs consumed by the public contain medicinal chemicals (BKO). This study aims to identify the presence of BKO prednisone in rheumatic herbs and its levels. This study took five types of samples of rheumatic herbs in Magelang area with different brands, namely samples of herbs A, B, C, D and E, which are available in capsule and powder form. Identification of prednisone in rheumatic herbs was carried out using thin layer chromatography (TLC) method with silica gel GF254 as stationary phase and ethyl acetate: chloroform mixture (4:1) as mobile phase. Quantitative analysis was performed using UV-Vis spectrophotometry with a maximum wavelength of 238.5 nm. The rf value of prednisone standard 0.42 was obtained and quantitative analysis showed that the prednisone content in sample B in the first replication was 3.22%, in the second replication was 2.18%, in the third replication was 2.23%.

Referensi

Anugraini, A., Syahbanu, I., & Melati, H. A. (2018). Pengaruh Waktu Sonikasi terhadap Karakteristik Selulosa Asetat Hasil Sintesis dari Sabut Pinang. Jurnal Kimia Khatulistiwa, 7(3), 18–26.

BPOM, R. (2023). Peraturan Badan Pengawas Obat dan Makanan Nomor 25 Tahun 2023 Tentang Kriteria dan Tata Laksana Registrasi Obat Bahan Alam.

BPOM Semarang. (2023, October 31). BBPOM Semarang Sidak Sarana Distribusi Obat Tradisional, Tertibkan Obat Tradisional Mengandung Bahan Kimia Obat. BPOM. https://semarang.pom.go.id/berita/bbpom-semarang-sidak-sarana-distribusi-obat-tradisional-tertibkan-obat-tradisional-mengandung-bahan-kimia-obat

Darmawati, A., Soebahagiono, S., Purwanto, D. A., Dharmawangsa, J., & Surabaya, D. (2016). Penentuan Kadar Parasetamol Dan Kofein Secara Simultan Menggunakan Spektrofotometri UV (Suatu Model Untuk Pembelajaran). Berkala Ilmiah Kimia Farmasi, 5(2), 11–14.

Fikayuniar, L. (2021). Identifikasi Kandungan Prednison Pada Jamu Rematik Dan Pegal Linu Di Karawang Barat. Jurnal Buana Farma, 1(1), 22–25. https://doi.org/10.36805/jbf.v1i1.44

Fitrianasari, R. D. P., Haresmita, P. P., & Agusta, H. F. (2023). Qualitative Analysis of Drug Substances in Rheumatic Jamu

Samples Using Thin Layer Chromatography. Medical Sains : Jurnal Ilmiah Kefarmasian, 8(3), 999–1008.

Kemala Sari, D., Hastuti, S., & Kesehatan Bhakti Mulia, P. (2020). Analisis Flavonoid Total Ekstrak Etanol Daun Seligi (Phyllanthus Buxifolius Muell. Arg) Dengan Metode Spektrofotometri UV-Vis Analysis of total flavonoid of ethanolic extract of seligi leaf (Phyllanthus buxifolius Muell. Arg) using UV-Vis Spectrophotometry Method. In IJMS-Indonesian Journal On Medical Science (Vol. 7, Issue 1).

Kemenkes RI. (2014). Farmakope Indonesia Edisi V.

Kemenkes RI. (2020). Farmakope Indonesia edisi VI. In Departemen Kesehatan Republik Indonesia.

Marwati, T. A., Nuraeni, L. H., & Desvita, W. R. (2021). Kesehatan Jiwa Ibu dan Obat Tradisional.

Pranoto, H., Rosmiati, M., Piksi, P., & Bandung, G. (2021). Tinjauan Proses Penentuan Prosedur Kadar Vitamin C Secara Kimia di PT. Tekad Mandiri Citra (Vol. 1, Issue 10). http://sosains.greenvest.co.id

Pratama Ridwan, I., Abdullah, R., & Sri Supriati, H. (2017). Identifikasi Fenilbutazon Dalam Jamu Rematik Yang Beredar Di Kota Manado Dengan Metode Kromatografi Lapis Tipis. Media Farmasi Indonesia, 12(1).

Primaharinastiti, R., & Helwandi, I. R. (2016). Three-Wavelength Spectrophotometric Method Validation For Determination Of Prednisone Tablet Containing Coloring Dyes. Proceeding ICMHS 2016 .

Wirastuti, A., Dahlia, A. A., & Najib, A. (2016). Pemeriksaan Kandungan Bahan Kimia Obat (Bko) Prednison Pada Beberapa Sediaan Jamu Rematik. Jurnal Fitofarmaka Indonesia, 3(1), 130–134. https://doi.org/10.33096/jffi.v3i1.172

Yanlinastuti, & Syamsul Fatimah. (2016). Pengaruh Konsentrasi Pelarut Untuk Menentukan Kadar Zirkonium Dalam Paduan U-Zr Dengan Menggunakan Metode Spektrofotometri UV-Vis.

Lisensi

Artikel ini berlisensi Creative Commons Attribution 4.0 International License.

Authors who publish with Sasambo Journal of Pharmacy (SJP), agree to the following terms:

Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Lisensi Creative Commons Atribusi 4.0 Internasional. This license allows authors to use all articles, data sets, graphics and appendices in data mining applications, search engines, web sites, blogs, and other platforms by providing an appropriate reference. The journal allows the author(s) to hold the copyright without restrictions and will retain publishing rights without restrictions.
Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgment of its initial publication in Sasambo Journal of Pharmacy
Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access).

Qualitative and quantitative analysis of prednisone chemical content in rheumatic herbs in Magelang Region

Penulis

DOI:

Diterbitkan:

Terbitan:

Kata Kunci:

Articles

##submission.downloads##

Cara Mengutip

Abstrak

Referensi

Lisensi

Terbitan Terkini

Informasi

Dikembangkan Oleh

Official Website Of

Jurnal Farmasi, Fakultas Kedokteran, Universitas Mataram

Contact Us

Official link

Share & Follow